The US space agency claims that Artemis I is the first in a line of intricate missions that would prepare the way for manned journeys to the Moon and Mars.
Orion will be attached to the Space Launch System (SLS) rocket that will launch Artemis I.
September 2 is the next available launch date, but whether or not another effort is made on that day will depend on how testing goes.
The organization's new Space Launch System megarocket and the Orion crew capsule will fly for the first time in Artemis 1 as a test flight.
The SLS rocket, capable of generating 8.8 million pounds of thrust, will liftoff as the most powerful rocket ever launched.
On October 10, Artemis I will come to a close after 42 days with the splashdown of Orion into the Pacific Ocean.
Future astronaut flights will use Artemis I to test the capabilities of the SLS rocket, Orion, and ground systems.